Clinical Nutrition 2008;27(2):289-296. View abstract. 2008;46(8):2728-2735. Oxidative stress in arteriogenic erectile dysfunction: prophylactic role of antioxidants. Savant, R. H., Banerjee, K., Utture, S. C., Patil, S. H., Dasgupta, S., Ghaste, M. S., and Adsule, P. G. Multiresidue analysis of 50 pesticides in grape, pomegranate, and mango by gas chromatography-ion trap mass spectrometry. J.Laryngol.Otol. J.Inflamm. A. Mercader-Ros M. T. Calín-Sánchez Á. Carbonell-Barrachina Á. Appl.Environ.Microbiol. Guo, C., Wei, J., Yang, J., Xu, J., Pang, W., and Jiang, Y. Pomegranate juice is potentially better than apple juice in improving antioxidant function in elderly subjects. Jafri, M. A., Aslam, M., Javed, K., and Singh, S. Effect of Punica granatum Linn. Effects of pomegranate juice on human cytochrome P450 2C9 and tolbutamide pharmacokinetics in rats. J.Chromatogr.Sci. Nutr J 2014;13:18. View abstract. Aviram M, Dornfeld L. Pomegranate juice consumption inhibits serum angiotensin converting enzyme activity and reduces systolic blood pressure. de Nigris, F., Williams-Ignarro, S., Sica, V., Lerman, L. O., D'Armiento, F. P., Byrns, R. E., Casamassimi, A., Carpentiero, D., Schiano, C., Sumi, D., Fiorito, C., Ignarro, L. J., and Napoli, C. Effects of a pomegranate fruit extract rich in punicalagin on oxidation-sensitive genes and eNOS activity at sites of perturbed shear stress and atherogenesis. Am J Cardiol 2005;96:810-4. View abstract. View abstract. Afaq, F., Zaid, M. A., Khan, N., Dreher, M., and Mukhtar, H. Protective effect of pomegranate-derived products on UVB-mediated damage in human reconstituted skin. 2009;47(2):125-132. cv.) Australian Journal of Basic and Applied Sciences 2009;3(4):4634-4643. Bagri, P., Ali, M., Aeri, V., Bhowmik, M., and Sultana, S. Antidiabetic effect of Punica granatum flowers: effect on hyperlipidemia, pancreatic cells lipid peroxidation and antioxidant enzymes in experimental diabetes. Study on antioxidant activity and extraction of polyphenols from pomegranate seed. View abstract. There is some research that investigated the effects of pomegranate extract on human lung cancer. Add onions, pomegranate molasses, carrots, and cumin. Rosuvastatin (Crestor) is broken down by the body in the liver. Proceedings of the 11th Biennial Meeting of the Society for Free Radical Research International, 2002 Feb:1-9. Br.J.Nutr. Serve fresh. Gonzalez-Sarrias, A., Larrosa, M., Tomas-Barberan, F. A., Dolara, P., and Espin, J. C. NF-kappaB-dependent anti-inflammatory activity of urolithins, gut microbiota ellagic acid-derived metabolites, in human colonic fibroblasts. View abstract. Hashemi, M., Kelishadi, R., Hashemipour, M., Zakerameli, A., Khavarian, N., Ghatrehsamani, S., and Poursafa, P. Acute and long-term effects of grape and pomegranate juice consumption on vascular reactivity in paediatric metabolic syndrome. J.Agric.Food Chem. View abstract. The objective of this study was to examine the anticancer effects of extract of Punica granatum (pomegranate) leaves extract (PLE) on the non-small cell lung carcinoma cell line A549, H1299 and mouse Lewis lung carcinoma cell line LL/2 in vitro, and explore its mechanisms of action. 2010;85(1):155-159. Clin Pharmacol Ther 2006;79:23. View abstract. View abstract. J Nutr 2001;131:2082-9. View abstract. View abstract. Int.J.Dermatol. A. View abstract. Am.J.Health Syst.Pharm. 2011;13(1):102. 2009;60 Suppl 2:197-210. 2010;10(3):174-180. View abstract. Fruit polyphenols and CVD risk: a review of human intervention studies. 2010;12(5):R195. Pomegranate is a lovely fruit to eat and which has the biology term called Punica granatum. Mattiello, T., Trifiro, E., Jotti, G. S., and Pulcinelli, F. M. Effects of pomegranate juice and extract polyphenols on platelet function. View abstract. Taking pomegranate juice along with medications for high blood pressure might cause your blood pressure to be too low.Some medications for high blood pressure include captopril (Capoten), enalapril (Vasotec), lisinopril (Prinivil, Zestril), ramipril (Altace), and others. Food Chemistry 2011;127(4):1444-1449. Drinking pomegranate juice might decrease how quickly the liver breaks down rosuvastatin (Crestor). Extract of Punica granatum inhibits skin photoaging induced by UVB irradiation. View abstract. But despite the wonderful health benefits of pomegranate, there are a few side effects that daily users should watch out for. Koh, K. H. and Tham, F. Y. View abstract. Bouroshaki, M. T., Sadeghnia, H. R., Banihasan, M., and Yavari, S. Protective effect of pomegranate seed oil on hexachlorobutadiene-induced nephrotoxicity in rat kidneys. Effects of consumption of pomegranate juice on carotid intima-media thickness in men and women at moderate risk for coronary heart disease. J.Sci.Food Agr. Adams, L. S., Zhang, Y., Seeram, N. P., Heber, D., and Chen, S. Pomegranate ellagitannin-derived compounds exhibit antiproliferative and antiaromatase activity in breast cancer cells in vitro. Torregrosa-García A, Ávila-Gandía V, Luque-Rubia AJ, Abellán-Ruiz MS, Querol-Calderón M, López-Román FJ. Clin Ther 2011;33:246-52. People allergic to pomegranate must avoid its consumption as it may result in rashes and itching. 2011;55(7):1096-1103. Emerg Med J 2010;27:74-5. Angiogenesis. Fitoterapia 2001;72(2):171-173. 2011;49(4):377-382. Dell'Agli, M., Galli, G. V., Bulgari, M., Basilico, N., Romeo, S., Bhattacharya, D., Taramelli, D., and Bosisio, E. Ellagitannins of the fruit rind of pomegranate (Punica granatum) antagonize in vitro the host inflammatory response mechanisms involved in the onset of malaria. Pantuck AJ, Zomorodian N, Belldegrun AS. Thomas R, Williams M, Sharma H, Chaudry A, Bellamy P. A double-blind, placebo-controlled randomised trial evaluating the effect of a polyphenol-rich whole food supplement on PSA progression in men with prostate cancer--the U.K. NCRN Pomi-T study. Parmar, H. S. and Kar, A. Antidiabetic potential of Citrus sinensis and Punica granatum peel extracts in alloxan treated male mice. Quiz: What Do You Know About Vitamin B12 Deficiency? Mohan, M., Waghulde, H., and Kasture, S. Effect of pomegranate juice on Angiotensin II-induced hypertension in diabetic Wistar rats. View abstract. Nutrients. Gheflati A, Mohammadi M, Ramezani-Jolfaie N, Heidari Z, Salehi-Abargouei A, Nadjarzadeh A. Endocr.Res. Langley P. Why a pomegranate? Sanchez-Lamar, A., Fonseca, G., Fuentes, J. L., Cozzi, R., Cundari, E., Fiore, M., Ricordy, R., Perticone, P., Degrassi, F., and De, Salvia R. Assessment of the genotoxic risk of Punica granatum L. (Punicaceae) whole fruit extracts. View abstract. Muscle strength. Wound healing activity of Malva sylvestris and Punica granatum in alloxan-induced diabetic rats. View abstract. 2011;2011:690518. 2009;31(6):522-531. Food Chem.Toxicol. Zhu, J. Yu L. Zhang L. Cui X. Ai H. Effect of water extraction from pomegranate peel on cardiac electrical activity of Bufo Bufo Gargarizans in vivo. View abstract. González-Sarrías A, Romo-Vaquero M, García-Villalba R, Cortés-Martín A, Selma MV, Espín JC. These are: Some people develop a certain kind of allergic reactions to fruits like pomegranate. View abstract. J Ethnopharmacol. Cerda, B., Ceron, J. J., Tomas-Barberan, F. A., and Espin, J. C. Repeated oral administration of high doses of the pomegranate ellagitannin punicalagin to rats for 37 days is not toxic. View abstract. Pomegranates side effects . Cardiol Young. Borochov-Neori, H., Judeinstein, S., Harari, M., Bar-Ya'akov, I., Patil, B. S., Lurie, S., and Holland, D. Climate effects on anthocyanin accumulation and composition in the pomegranate (Punica granatum L.) fruit arils. J Nutr Biochem 2005;16(9):570-576. 2010;21(8):717-725. Let it simmer on low heat. View abstract. Asian Journal of Chemistry 2011;23(7):3131-3234. View abstract. - Bibel, 2 Cor. Drugs Exp.Clin.Res. Moneam NM, el Sharaky AS, Badreldin MM. Sumner MD, Elliott-Eller M, Weidner G, et al. View abstract. Bachoual, R., Talmoudi, W., Boussetta, T., Braut, F., and El-Benna, J. Early research shows that taking pomegranate extract by mouth does not prevent sunburn. J.Agric.Food Chem. Das, A. K., Mandal, S. C., Banerjee, S. K., Sinha, S., Das, J., Saha, B. P., and Pal, M. Studies on antidiarrhoeal activity of Punica granatum seed extract in rats. Indian J.Biochem.Biophys. View abstract. View abstract. The therapeutic properties of the pomegranate fruit, peel, root, and leaves have been reported in various studies (Prasad & Kunnaiah, 2014; Zarfeshany, Asgary, & Javanmard, 2014). View abstract. Auerbach L, Rakus J, Bauer C, et al. 2001;78(1):85-87. View abstract. View abstract. 2010;67(5):511-516. Martin, K. R. Krueger C. G. Rodriquez G. Dreher M. and Reed J. D. Development of a novel pomegranate standard and new method for the quantitative measurement of pomegranate polyphenols. Pomegranate has a number of benefits, but it may lead to some side-effects on the body, some of which are listed below: Excessive consumption of pomegranate leads to gastric problems. Sorokin AV, Duncan B, Panetta R, Thompson PD. Int.J.Food Sci.Nutr. 1995;20(9):556-8, 576, inside. Mutat.Res. Acta Horticulturae 2009;818:257-264. Wright, H. and Pipkin F. B. Pomegranates (Punica granatum), kiwifruit (Actinidia deliciosa) and blood pressure: a pilot study. BMC.Complement Altern Med 2009;9:27. Pomegranate extract improves maximal performance of trained cyclists after an exhausting endurance trial: A randomised controlled trial. International Journal of Fruit Science 2009;9(3):226-231. View abstract. (Tokyo) 2006;52(5):383-388. Research Journal of Biological Sciences 2010;5(8):561-564. 10-8-2008;269(2):262-268. 1996;53(3):143-147. Along with its health benefits, pomegranate is also known for some of its side effects. Proceedings of the Nutrition Society 2010;69(1):95. Oncol.Rep. Eur J Clin Nutr 2006;60:245-53. 2009;47(6):1221-1230. Potential antiparasitic activity of pomegranate extracts against shistosomules and mature worms of Schistosoma mansoni: in vitro and in vivo study. View abstract. View abstract. 2010;75(7):C626-C632. Influence of fruit juices on drug disposition: discrepancies between in vitro and clinical studies. Drinking pomegranate juice does not seem to improve symptoms or breathing in people with this condition. Part 182 -- Substances Generally Recognized As Safe. Scientia Agricultura Sinica 2009;42(11):4035-4041. View abstract. 2010;29(4):668-673. 2011;78(3):1013-1017. For example, Li et al (2016) analysed the effects of pomegranate leaves … Kuang, N. Z., He, Y., Xu, Z. View abstract. We use cookies to ensure that we give you the best experience on our website. View abstract. View abstract. It might also increase how long cycling can be done. J.Agric.Food Chem. View abstract. 9-24-2008;56(18):8704-8713. The fruit is delicious and juicy, and it can be eaten straight or extracted for its juice. BMJ 2000;321:1153-4. Therefore, individuals using these drugs should consult their doctor before consuming it on a regular basis. View abstract. 3. Devatkal, S. K., Narsaiah, K., and Borah, A. Anti-oxidant effect of extracts of kinnow rind, pomegranate rind and seed powders in cooked goat meat patties. J.Ethnopharmacol. 2011;25(11):1059-1066. McFarlin, B. K., Strohacker, K. A., and Kueht, M. L. Pomegranate seed oil consumption during a period of high-fat feeding reduces weight gain and reduces type 2 diabetes risk in CD-1 mice. View abstract. View abstract. View abstract. Fazeli, M. R., Bahmani, S., Jamalifar, H., and Samadi, N. Effect of probiotication on antioxidant and antibacterial activities of pomegranate juices from sour and sweet cultivars. Murthy KN, Reddy VK, Veigas JM, Murthy UD. Maturitas 2008;61(1-2):181-193. Salgado, L. Melgarejo P. Meseguer I. and Sánchez M. Antimicrobial activity of crude extracts from pomegranate (Punica granatum L.). Boll Soc Ital Biol Sper 1989;65:385-90. View abstract. Journal of Food Science 2011;76(4):606-611. It has been discovered that pomegranate can slow down the deterioration of cartilages around the bones. Nitric.Oxide. Effects of pomegranate juice consumption on myocardial perfusion in patients with coronary heart disease. Evid.Based.Complement Alternat.Med. There are rarely any troublesome side effects when using pomegranate leaf in this manner. Utture, S. C., Banerjee, K., Dasgupta, S., Patil, S. H., Jadhav, M. R., Wagh, S. S., Kolekar, S. S., Anuse, M. A., and Adsule, P. G. Dissipation and distribution behavior of azoxystrobin, carbendazim, and difenoconazole in pomegranate fruits. J Ethnopharmacol 1999;66:11-7. Hayouni, E. A., Miled, K., Boubaker, S., Bellasfar, Z., Abedrabba, M., Iwaski, H., Oku, H., Matsui, T., Limam, F., and Hamdi, M. Hydroalcoholic extract based-ointment from Punica granatum L. peels with enhanced in vivo healing potential on dermal wounds. Pomegranate Side Effects. View abstract. 2009;23(5):531-536. Morton J. Pomegranate. J Agric Food Chem 2-8-2006;54(3):980-985. View abstract. Allergy to pomegranate (Punica granatum). High blood pressure ( hypertension). View abstract. View abstract. View abstract. View abstract. Antioxidant activity of pomegranate juice and its relationship with phenolic composition and processing. Ilbey, Y. O., Ozbek, E., Simsek, A., Cekmen, M., Somay, A., and Tasci, A. I. Pomegranate (Punica granatum L.), one of the oldest known edible fruits, is nowadays broadly consumed throughout the world. J Clin Pharmacol 2007;47:286-94. Tripathi SM, Singh DK. De, M., Krishna, De A., and Banerjee, A. Sprinkle with pomegranate seeds. Cook until carrots are tender. View abstract. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. View abstract. New studies are just now showing how powerful an anti-aging agent pomegranate truly is. pii: E1593. J Natl Cancer Inst 2003;95:346-8. 2-Methyl-pyran-4-one-3-O-beta-D-glucopyranoside isolated from leaves of Punica granatum inhibits the TNFalpha-induced cell adhesion molecules expression by blocking nuclear transcription factor-kappaB (NF-kappaB). 2009;46(1):106-111. J Agric Food Chem 5-21-2003;51(11):3493-3501. Beltz, J. McNeil C. Fisher M. Shaw P. Breece L. Sellers T. andBrown K. Investigation of the antihyperalgesic effects of the pomegranate extract ellagic acid. Biofactors 2007;31(1):17-24. Asian Pacific Journal of Tropical Medicine 2010;3(9):687-690. Seeram, N. P., Zhang, Y., McKeever, R., Henning, S. M., Lee, R. P., Suchard, M. A., Li, Z., Chen, S., Thames, G., Zerlin, A., Nguyen, M., Wang, D., Dreher, M., and Heber, D. Pomegranate juice and extracts provide similar levels of plasma and urinary ellagitannin metabolites in human subjects. View abstract. Esmaillzadeh A, Tahbaz F, Gaieni I, et al. Pomegranate juice supplementation in chronic obstructive pulmonary disease: a 5-week randomized, double-blind, placebo-controlled trial. Br.J.Nutr. Koyama, S., Cobb, L. J., Mehta, H. H., Seeram, N. P., Heber, D., Pantuck, A. J., and Cohen, P. Pomegranate extract induces apoptosis in human prostate cancer cells by modulation of the IGF-IGFBP axis. Cvd risk: a review Ranchordas MK, Johnson E, Denning J, al! Power fruit, may improve triglycerides and “ good ” ( HDL ) cholesterol levels ' Society 2009 86... Disease activity in patients with the skin condition of rats with nephrolithiasis induced by ethylene glycol on Natural medicines Database. 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