She keeps getting infections in her anal gland area. Hes been to Cornell, and we have tried just about everything. Apoquel scares me with with how quickly my frenchie started getting infections, instability, diarrhea and was still mildly itchy (probably from the yeast infections she was getting). Required fields are marked *. After ten years of fighting severe inside of the paws allergies, to the point that this 150# dog could barely walk, I was elated that something finally worked. We just make sure to take him out frequently to be safe. My 7 year old male GSD has been on apoquel for 2+ years now for horrible scratching due to atopic dermatitis. I began coming in from work and finding that he had been sick in several spots. While the exact mechanism of action is not known, it is thought that Apoquel works by inhibiting the activity of Janus kinase enzymes, which are important in signal transduction in many cells, including those involved in the allergic response. 00 for 2 mths. If you give your dog Apoquel and Benadryl at the same time, be sure to monitor them closely for any signs of drowsiness or fatigue. Last June 2016 our vet prescribed Apoquel for our 8 year old Shih Tzu for her itching. Great! For the past month or so he just wasnt right; lethargic, increased ear infections and two weeks ago while chasing a ball it looked as though a linebacker took the legs out from under him, but only on his right side. If you are into animal welfare, you probably should stay away from those supplements. He had an ultrasound and it was determined it was likely due to the Apoquel, and he was diagnosed with liver disease. Atopic dermatitis is one of the most common allergies in dogs, affecting approximately I started her on 1/2 tab once a day every day for the last month and 1/2. JA: Hi there. My dog had been on Prednisone several times before and he always had excessive urination but never had an accident in the house. I have also found that by wiping his feet with a damp towel after he comes in from outside, there is far less itching and scratching. But I will never use these medications again and will find alternative methods of controlling the infections, i.e. Lately I have been trying Vitamin C which has some antihistamine qualities, and his itching is decreasing. I rescued a red male lab/pit mix who was sick with kennel cough. 5 days on Apoquel and she went to the kennel. Our present vet had him on prednisone off and on and it seemed to work but we were all worried about long term effects. He actually unlocked a sliding glass door aggressively scratching at the walls and door jam and got out and was digging under the fence when our neighbor whom we called came and put him back in the house. After reading the comments here I will not be continuing on Apoquel. I was also giving him baths with malaseb or microtek shampoo every few days. In simple terms, apoquel changes how the immune system acts. DrugBank Accession Number. It was prescribed by his dermatologist. As I write this I just want everyone to know.the drug may stop the itching as it did with my dog, but it allows the immune system to weaken and your dog wont be able to fight off the most basic thing: fungus. In my opinion the drug trials were inadequate (300 dogs, many of which dropped out), and this drug is DANGEROUS. Janus kinase Inhibitors are on the market for the treatment of autoimmune diseases in humans including Xeljanz and baricitinib (Olumiant Lilly) for oral treatment of adults with moderately to severely active rheumatoid arthritis (RA). associated with allergic dermatitis and for the control of atopic dermatitis. The drug has been wonderful for the most part. DO NOT GIVE THIS POISON TO YOUR PET. He has had these issues his whole life (and in the last two years we have moved two hours away). The treatment can be very effective. THIS STUFF OUT LIKE CANDY However, his alk phos was literally off the chart and we could not get it down. My 8 year old beagle/basset was put on Apoquell for itching on 10/13/16 and died this morning from liver failure and pancreatitis. Suddenly she was sneaking off to the back bedroom to go in-between. On the sixth day he could barely walk and we took him to an emergency vet hospital. In a study, dogs were treated with Apoquel for more than 2 years. I am seriously thinking this drug is to blame. He was gone 6 days later. Zyrtec is safe for dogs as long as you follow the direction of your vet and a few safety guidelines. Within a day he began acting different lethargic and mildly aggressive but he never stopped itching. By week 7 he was having diarrhea and was put on Metronidazole. nothing major yet -except she doesnt The US Food and Drug Administration (FDA) has not placed any time restrictions on the use of Apoquel. We have to be careful sometimes we give this drug because it eases our mind about our dog itching and being uncomfortable . A typical dose is 1 mg per pound in dogs every 6-8 hours. I read information about the side effects and took him off the medication about a month ago. quality of life for both the dog and its owner unless they are controlled with effective I find that hydroxyzine work best for my girl but that requires an Rx. Carprofen was previously used in human medicine for over 10 years (1985-1995). So after $1,100. Im wondering if anyone has had luck with a very low dose achieving less itching with less side effects? So, on Apoquel she went. We purchased a bottle with 70 tablets for $137.20 in hopes that this would provide some relief. The number of these papillomas appeared to be increasing. In April he received Lyme vaccine and shortly thereafter developed skin infection requiring steroids. Thankful that I followed my instinct as the vet made us very uncomfortable with his rapid sales pitch. However, after only 5 days on the drug, he became lame with a painful right paw and a painful back leg. Baytril a huge heavy hitter in antimicrobials, but scant other basic antibiotics on your shelf that could be used as a first line. And only started happening when she went back on the drug. However, after about 2 months on the medicine he started urinating in the house. Even when it was off the market, I had a doctor who had a source for me to continue getting the drug. She has now had two seizures. I am so grateful to have her but feel bad as she has to take 570 pills every month plus liquid medication, mostly due to her size. Instead of continuing to be a veterinarian, helping those innocent animals, and even keeping them from going to other veterinarians that may not explain the risks with medications, you quit, to sell supplements and offer a one sided view. They even called the company and the company denied having dogs with bladder infections when clearly it causes them. I would hate to think that the profit that vets make from exclusively distributing Apoquel out shines their professional duty to be appear of these serious adverse events especially given my case where the veterinarian started prescribing Apoquel in December 2016 and started to see these parasitic growths appear within 3 months of initiation of therapy. The only saving Grace from all of this is I got to whisper in her ear, Its OK baby Girl Mommas got you. The only thing the bw showed was that his body was basically starving. NO. I dont remember her specific white cell counts. diarrhea, vomiting, and lethargy that resolved spontaneously in 90% of cases and did not So hard to do and they dont even care as long as they make their money at $200 a bottle take it vantage of court animals and people. Theyll be able to help you figure out the best course of action for your individual dog. Please let me know what I can do to help get this drug off the market. Dr. suggested apoquel which I paid 120. My vet has referred us to a vet specialist, which I hear is very expensive. The Vitamin C dose is 100mg per 10lbs twice daily. We brought him back to the vet on July 11, 2017 to evaluate at which time an antibiotic was prescribed and again a new prescription for 70 Apoquel 5.4mg tablets at a cost of $126.00 for the Apoquel. Every dog is different, so you have to try different foods; there is not just ONE right food. of the development of severe pyoderma (after day 19) and one dog withdrew because of the and said everything is normal, probably will never happen again. 4.Antihistamines- both natural and conventional. My yellow lab took apoquel with great successso we thought. The short answer is yes, it is safe to give your dog antihistamines alongside Apoquel. My daughter stated she is doing this head and leg thing every morning the past 3 weeks. In fact, antihistamines are quite often used to treat skin allergies in dogs. Very unlike him and the bowl belongs to a dog that visits a lot and he is head over heels in love with. What is the lesser of the two evils? Having read a lot of comments on this article I have my own story with Apoquel. Im starting to think all these different vaccines may not be such a good idea. Remember just a 1/4 or less amount that a human would take for the vitamins unless I mentioned an amount the vet gave me. The study she pulled said 10% of dogs will develop these tumors with Apoquel. The other option would have probably would have been a lot worse. The vet kept urging us to put her on it, that the side effects would be mild and should disappear. Unknown: No interaction information available. He then became very lethargic, drinking quite often, and urinating in large amounts. When I took him to the vet, he had 106 degree temp (above 102.5 in dogs is a fever) and they couldnt figure out where the infection was. She went into Cardiac Arrest and flat lined. Just wish I could find it cheaper but she is well worth the $93/month I spend on her! I was suspect of this drug before I read the study. It has been determined that it is more than likely the combination of the Apoquel and the steroid injection.. But other OTC antihistamines may have added decongestants, which are not safe for dogs. After 1 month she was reduced to 1 in the morning. Im just sick. He also gets half a Zyrtec morning and night. It worked almost immediately. Here is my dilemma. they will run more blood test on him tomorrow and see if his blood counts go down if not we have to decide to keep him or put him down. Active and happy. Despite providing the vet center with a copy of my letter to Zoetis and their request to have the vet contact them to discuss this AE, as of 9-6-19 the vet has not contacted them. As I write this my 4 month old puppy is in ICU getting I.V. I have an 11 year old pit bull that has had skin allergies for years before our vet put him on Apoquel. I hate to consider long term effects of this drug. They have been developed so as not to cause drowsiness. Unbelievable!!! I now wonder if he had environmental allergies. No vet should use this drug!!! Last spring, his scratching caused the side of his face to look like he had been attacked and lost the fight. On the FDA report you wrote of earlier, Apoquels side effects arent listed only their FDA approvals are there. His armpits had not grown hair in two years, despite constant Benadryl dosing. As luck would have it, I did a research on both meds as I normally do with any meds, and as fate would have it came upon this site. We had tried everything, including allergy shots. Noticeably happier and energetic. I thought it was due to me not being able to have play time (because of major surgery I had). After 2 further doses he went berserk again. As with any medication, its always best to start with the lowest possible dose and increase gradually if necessary. my newfie takes 1 1/2 tabs. However, it can be used for food allergies as well. I even had to duct tape socks to his feet. We had to use the Apoquel because he needed surgery for a torn ACL and couldnt use prednisone. No more. Hydroxyzine (brand names: Atarax, Vistaril, Masmoran, Multipax) is an antihistamine used to treat allergic and itchy conditions or as a sedative/tranquilizer. Has been on short term antibiotics and steroids for secondary skin infections. DB00821. My 2 1/2 year old French Bulldog, Philippe, has been on Apoquel for a few months. People need to look at tbeir vetwhat has been tried first. I took her to the vet and they ran tests which all came back negative. Treating dogs with antihistamines can take some trial and error as each animal reacts very differently. He seemed confused and his coordination was way off. He is about 3 yrs old. Topical Solutions Use a topical product that works to calm the source of the itchy skin and inflammation. She told me not to take the 2 bp meds and antistroke meds the traditional vet prescribes that diagnoses the kidney problem. I feel this is a very damaging drug with limited safety studies. As always, if you have any further questions or concerns, please do not hesitate to contact us. Apparently either your company representative, the veterinarians or both are not being made aware that this serious adverse event is occurring in dogs exposed to Apoquel with long term use. Two days later he was at deaths door. Never told that it destroyed the immune system or the side effects. Tried Benadryl which worked some, but she would get flares. The dogs doctors dont feel Apoquel is the cause, but they are going about the practice of medicine to make a determination, not jumping on your band wagon. When we moved my new vet recommended the new drug that was having great results on allergies in dogs Apoquel. This progressed until he had weeping sores under his arms and in his groin that would get infected. this medication is good for a short period of time, but the side affects are far more dangerous, Hello, I have 2 dogs, 45 kg and 8 kg. He had stopped eating and drinking. Any suggestions for options other than what I have already tried, in order to get him off Apoquel? We will look at these later in this article. He never does that, he always tells me when he has to go out. You can contact Zoetis Inc at 1-888-963-8471. Just like an earlier person wrote my dog was howling during the seizure. I looked up side effects and was horrified. Maybe more so because now I know that he had no tumor, nothing anywhere, it was the APOQUEL. I had actually stopped the Apoquel about 3 days before the first seizure because I felt it was making her sick. 1 [deleted] 8 yr. ago I am trying the drug today onwards for my baby and Im hoping for good results and hopefully no side effects will let you know. It also isnt working as well on her skin this time as it did when she was first on it. I should have typed EFFECTS not AFFECTS. Just yesterday his lab panel showed elevated liver enzymes and he was transferred to a 24 hour emergency hospital. He is still kind of quiet and sleeping a lot but at least it seems like he is getting back to be himself again. It is just like our medication do you honestly think the side effects are listed for us ? She was done with the medication on Oct 31 and her hair was falling out and She started developing lymph nodes in her chest area. They destroyed his stomach, his stomach was trembling, he lost appetite on and off, the last day when he collapsed was because he was not able to breathe due to a mass near his heart coming from the spleen had formed from taking this SHIT. Great, or so I thought. I have to wonder if this caused or even added to these problems. I started my 9 year old Shih Tzu on APOQUEL 6 weeks ago and have had two blood panels done. He cried and was unable to walk correctly. At first it was great because it suppressed the itching. The itching has come back full blown .. bumps swollen paws ect. Lets see the drug company Zoetis reported this: Zoetis Reports Fourth Quarter and Full Year 2014 Results This is a awful drug. After reading all the comments, I have decided not to take the risk of harming my dog more by this drug. She went on this medication because she got extremely itchy from going into the lake. He now has a tumor on his neck ( just removed and sent for histopatholgy). Customer: Hi, can a dog be on cytopoint, benadryl and apoquel at the same time? If the wind blows the wrong way she starts breaking out. I noticed that she did have some more frequent urination and she had a kind of balance issue, she just wasnt acting right when she first started on the apoquel. One pill thats all she got! Keep fighting the good fight! Vet was not aware of all these side affects because I had asked right after starting her. I have her on flea meds year round, no fleas. management. Again Please do not give your animal this medicine, Your email address will not be published. which is fine with me. The only good thing is that her appetite is still really good. Can you give a dog Zyrtec and Apoquel together? That seemed to set him off so gave him a little more for a few days and also ketaconazole. I forgot you add the above food mix to 3kg of chicken or turkey mince. She also has a running nose at times and when she is laying down and resting she sounds like she is congested. Your vet will work to determine the appropriate dosage according to a few factors. I have photos of that food really odd changes!!! Both drugs are relatively safe, so the risk of side effects is low when they are used together. After allergy, blood and urine tests she put him on Apoquel, 2 times a day for 1 week and then one pill in morning. After 30 days of use, He doesnt show any signs of them. I cant wait to see what the blood work will reveal though, it will be interesting. We give her oatmeal baths and it dont help. My dog is a 2 and 1/2 year old yorkies. On allergies in dogs Apoquel Apoquel together to the vet gave me week 7 he was transferred a... Always, if you are into animal welfare, you probably should stay away from those.!, after only 5 days on the drug has been tried first 300 dogs many! Relatively safe, so the risk of harming my dog had been sick in several.... 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